Dechun Feng Selected Research

Concanavalin A

1/2021	Interleukin-20 exacerbates acute hepatitis and bacterial infection by downregulating IκBζ target genes in hepatocytes.
1/2020	Kupffer cells promote T-cell hepatitis by producing CXCL10 and limiting liver sinusoidal endothelial cell permeability.
1/2019	Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids.
1/2015	Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences.
6/2014	STAT4 knockout mice are more susceptible to concanavalin A-induced T-cell hepatitis.
3/2014	Opposing effects of prednisolone treatment on T/NKT cell- and hepatotoxin-mediated hepatitis in mice.
6/2010	Selection of reference genes for quantitative real-time reverse transcription-polymerase chain reaction in concanavalin A-induced hepatitis model.
4/2009	Vasoactive intestinal peptide attenuates concanavalin A-mediated liver injury.
2/2009	Stearoyl-CoA desaturase 1 deficiency protects mice from immune-mediated liver injury.
12/2008	Tetrandrine protects mice from concanavalin A-induced hepatitis through inhibiting NF-kappaB activation.

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Dechun Feng Research Topics

Disease

27	Inflammation (Inflammations) 01/2022 - 08/2008
14	Hepatitis 01/2021 - 02/2008
10	Liver Diseases (Liver Disease) 01/2021 - 08/2011
9	Fatty Liver 01/2020 - 02/2008
6	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 04/2011
6	Fibrosis (Cirrhosis) 01/2021 - 04/2011
5	Bacterial Infections (Bacterial Infection) 01/2021 - 02/2015
4	Acute Liver Failure (Fulminant Hepatic Failure) 01/2022 - 09/2014
4	Non-alcoholic Fatty Liver Disease 01/2021 - 01/2020
4	Liver Neoplasms (Liver Cancer) 11/2019 - 10/2013
4	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2017 - 08/2011
3	Alcoholic Hepatitis 01/2022 - 03/2014
3	Infections 01/2021 - 07/2012
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 09/2009 - 08/2008
2	Reperfusion Injury 01/2021 - 05/2014
2	Ischemia 01/2021 - 05/2014
2	Neoplasms (Cancer) 01/2021 - 10/2019
2	Acute-On-Chronic Liver Failure 09/2020 - 01/2020
2	End Stage Liver Disease 01/2020 - 10/2018
2	Alcoholic Fatty Liver 01/2020 - 01/2018
2	Binge Drinking 01/2019 - 03/2018
2	Obesity 03/2018 - 01/2015
2	Autoimmune Hepatitis 06/2014 - 03/2014
2	Multiple Sclerosis 12/2008 - 08/2008
1	Disease Progression 01/2022
1	Colitis 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Leukemia 11/2020
1	Hypoxia (Hypoxemia) 01/2020
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2020

Drug/Important Bio-Agent (IBA)

13	Interleukin-22 (IL-22)IBA 01/2021 - 01/2012
12	Ethanol (Ethyl Alcohol)IBA 01/2022 - 08/2011
12	Concanavalin AIBA 01/2021 - 02/2008
8	CytokinesIBA 01/2021 - 08/2011
6	InterleukinsIBA 01/2021 - 08/2011
6	Proteins (Proteins, Gene)FDA Link 01/2020 - 12/2008
4	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2022 - 09/2014
4	Interleukin-6 (Interleukin 6)IBA 01/2021 - 02/2015
4	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2021 - 04/2011
4	ChemokinesIBA 09/2020 - 10/2019
3	RNA (Ribonucleic Acid)IBA 01/2022 - 10/2016
3	Mitochondrial DNA (mtDNA)IBA 01/2020 - 01/2017
3	Oxidoreductases (Dehydrogenase)IBA 01/2020 - 10/2017
3	Messenger RNA (mRNA)IBA 10/2019 - 12/2008
2	Nonesterified Fatty Acids (NEFA)IBA 01/2022 - 10/2015
2	neutrophil cytosolic factor 1IBA 01/2022 - 03/2018
2	E-SelectinIBA 01/2022 - 01/2017
2	interleukin 20 (IL-20)IBA 01/2021 - 01/2021
2	InterferonsIBA 01/2021 - 08/2011
2	Neutralizing AntibodiesIBA 01/2020 - 10/2015
2	Phosphotransferases (Kinase)IBA 01/2020 - 01/2017
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2015
2	Lipocalin-2IBA 10/2018 - 02/2015
2	Digoxin (Digitek)FDA LinkGeneric 05/2018 - 01/2018
2	Pyruvate KinaseIBA 05/2018 - 01/2018
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2018 - 01/2017
2	NADP (NADPH)IBA 03/2018 - 10/2017
2	EnzymesIBA 01/2017 - 01/2012
2	Interferon-gamma (Interferon, gamma)IBA 10/2016 - 10/2013
2	interleukin-22 receptor (IL-22R)IBA 08/2013 - 09/2012
2	gamma-Aminobutyric Acid (GABA)IBA 09/2009 - 12/2008
2	LipidsIBA 02/2009 - 02/2008
2	NF-kappa B (NF-kB)IBA 12/2008 - 09/2008
1	AdipokinesIBA 01/2022
1	AMP-Activated Protein KinasesIBA 01/2022
1	MicroRNAs (MicroRNA)IBA 01/2022
1	paquinimodIBA 01/2022
1	RetinoidsIBA 01/2021
1	Hydroxysteroid DehydrogenasesIBA 01/2021
1	LipopolysaccharidesIBA 01/2021
1	Neomycin FDA LinkGeneric 01/2021
1	Interleukin-13IBA 01/2021
1	Triglycerides (Triacylglycerol)IBA 01/2021
1	Poly I-CIBA 11/2020
1	Adenosine Monophosphate (AMP)IBA 11/2020
1	LigandsIBA 09/2020
1	p38 Mitogen-Activated Protein KinasesIBA 01/2020
1	PPAR alphaIBA 01/2020
1	CCAAT-Enhancer-Binding ProteinsIBA 01/2020
1	Interleukin-8 (Interleukin 8)IBA 01/2020
1	eflepedocokin alfaIBA 01/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2020
1	Mitogen-Activated Protein KinasesIBA 01/2020
1	MAP Kinase Kinase Kinase 5IBA 01/2020
1	Streptococcus intermedius intermedilysin proteinIBA 01/2020
1	Caspase 3 (Caspase-3)IBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 11/2019
1	XenobioticsIBA 01/2019
1	CorticosteroneIBA 01/2019
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2019
1	B7-H1 AntigenIBA 01/2019
1	CC ChemokinesIBA 01/2019
1	AcetaldehydeIBA 01/2019
1	GlucocorticoidsIBA 01/2019

Therapy/Procedure

7	Therapeutics 01/2022 - 12/2008
2	Intraperitoneal Injections 01/2020 - 10/2018
2	Hepatectomy 02/2015 - 01/2009
1	Precision Medicine 01/2020
1	Liver Transplantation 01/2020
1	Immunotherapy 01/2019